Volume 10 | Issue 1 | January

 Abstract

Cr (III), Mn(III),Fe(III)and M(III) complexes with a Schiff base derived from 2-amino-4-ethyl-5-hydroxybenzaldehyde and thiocarbohydrazide were synthesised and characterised using a variety of techniques, including elemental analysis (C, H,N), molar conductance measurements, magnetic measurements, and electronic, mass, and IR spectral studies. A five-coordinated square pyramidal geometry was suggested for all the complexes based on these findings. The Schiff base ligand and the complexes were also evaluated for antibacterial activity (against Escherichia coli, Staphylococcus aureus, Pseudomonas aeruginosa, Bacillus megaterium, and the fungus Kluyveromyces fragilis, Rhodotorula rubra, Candida albicans, and Trichoderma reesei). Additionally, an attempt was made to correlate the complexes' antimicrobial activity with their geometry. Each complex was shown to be less active against E. coli, S. aureus, and P. aeruginosa. Although the Cr (III) complex had the greatest antibacterial action, the ligand alone was shown to be potent against the fungus T. reesei.

Licence: creative commons attribution 4.0

  License

Creative Commons Attribution 4.0 and The Open Definition

 Keywords

Schiff Base; 2-amino-4--ethyl-5-hydroxybenzaldehyde; thiocarbohydrazide; antimicrobial activity.

  License

Creative Commons Attribution 4.0 and The Open Definition